
Polynucleotides are regenerative injectable treatments designed to improve overall skin quality by supporting the skin’s natural repair and renewal processes. They work by stimulating collagen production, improving hydration and elasticity, and helping to restore healthier, stronger skin from within.
Read MoreAt Nuvo Aesthetics, Nurse Clinic Owner Laura carefully selects treatments backed by innovation, safety, and results, which is why we now offer REJURAN® skin rejuvenation treatments. Originating from South Korea, REJURAN® is an advanced polynucleotide treatment formulated to improve skin texture, firmness, hydration, acne scarring, sun damage, and early signs of ageing, while promoting a healthier, more radiant complexion.
REJURAN® treatments can also be used in delicate areas such as the under-eyes, helping to improve crepey skin, fine lines, and skin laxity around the eye area.

Polynucleotides are suitable for all ages. As the product is derived from animal sources, it is unsuitable for vegetarians, vegans, or those with fish allergies. It is also not recommended during pregnancy or breastfeeding, similar to other injectable treatments.
The initial treatment consists of three sessions, spaced two to three weeks apart. Follow-up treatments are recommended every six months to maintain optimal results. Polynucleotide injections can be combined with other treatments depending on your concerns.
Results may start to appear four weeks after the first treatment, with the most noticeable improvements occurring two months after the second treatment.
Pain is minimal due to the use of topical numbing cream and fine needles. You can resume normal daily activities right after treatment. Small bumps where the product was injected typically dissipate within hours or days. Redness, bruising, or swelling may occur. Laura Arena, Nuvo Aesthetics’ Nurse Injector, uses a specific needle called the “TSK invisible needle,” which minimizes the risk of bruising.
30 mins
Treatment Time
Minimal
Downtime
6 - 12 months
Duration Of Results
1 - 2 weeks
Until Results Seen
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